Talk Drug

Needs no exercise, no dieting, only take one injection you many loss weight. What’s an exciting news for obese people! As reported, U.S. scientists have completed the test upon small mice successfully, so may in the near future, this drug may come true really there! This is really a goode news for obesity.

Millions of Americans want to lose weight. On their treadmills and over their salads, they dream of a quick fix that doesn’t require excessive dieting and exercise.

And the hope that those dreams could become reality got a boost this week when team of researchers at Indiana University released a study Monday in the online journal Nature Chemical Biology that showed that two natural hormones combined into a single drug suppressed appetite and increased metabolism — in rodents, anyway.

“There’s a global epidemic of obesity,” said Richard DiMarchi, chair of the chemistry department at Indiana University in Bloomington and the study’s lead researcher. “Our focus is finding therapies to lower body weight and treat diabetes.”

A single injection of the drug decreased the rodents’ body weight by 25 percent — and fat mass by 42 percent – after one week.

Post by: Talk Drugs

In order to lose weight, people may do anything at any cost, do much exercise, take a diet, pay much money to buy diet pills and so on. Many people think that taking diet pills is enough, but those diet pills introduced in ads will take effect really?

Losing weight is a behavior for the purpose to reduce one’s excessive body fat and body weight. The key index is BMI, and there are many methods, among which diet is the core way, and exercise is a supporting, taking drugs is an enforcement manner.

A German study found that most of the weight loss drugs is only act as a placebo, people who want only to lose weight through diet pills is not possible.

The vast majority of over-the-counter weight loss aids do not work, according to a recent study by nutritional experts in Germany. Research published by the Institute for Nutrition and Psychology at the University of G?ttingen found that none of the nine best selling weight-loss supplements sold in pharmacies in Germany had any effect beyond acting as a placebo.

Over-the-counter weight loss supplements are big business. Billions of dollars are spent each year by people hoping to find the miracle supplement that will help them lose weight.

A summary of studies led by Dr Thomas Ellrot – head of the Institute for Nutrition and Psychology at the University of Gttingen Medical School was presented to the International Obesity Conference in Stockholm on Monday (July 12, 2010). It found that the nine best selling over-the-counter weight-loss supplements acted only as a placebo.

“I think the message for the consumer is very important because lots of people go in to pharmacies and spend a lot of money for weight-loss supplements and this money is thrown out of the window. Because, it is just placebo effect, and the placebo effect could be, you could get this for much less money.”

The eight-week study divided 189 overweight people in to two groups. One group was given the daily recommended dosage of weight-loss supplements. The other group was given a placebo. The real products were repackaged to make them look neutral. The people given the real products were also asked to follow the instructions provided by the manufacturer, including dosage and additional dietary recommendations.

The average weight loss for the group given the placebo was 1.2kg over the 8 week period. The people in the group given weight loss supplements had an average weight loss of between 1kg and 2kg but, according to Ellrot, none of the supplements outperformed the placebo.

The study used a range of over-the-counter supplements that varied widely in price. “That cost range was incredible. Between a couple of Euros for two months of treatment compared to the most expensive supplement that cost close to 300 Euro (377 US dollars) per two months of supplement use. And that is 300 Euros for, like, nothing.”

At the Berlin Apotheke pharmacy in central Berlin a variety of weight loss supplements are displayed and sold. Some are essentially soy protein products designed to help people stay on diets while still getting enough protein. Others claim they include ingredients that claim to block the absorption of fat by the body.

According to the in-house nutritionist, Alexandra Schellbach the soy protein products do not make people lose weight, but they do help users feel better when they are on a diet.

“Many people believe in that wonder pill that gives people a perfect body without exercise, without the diet and without changing their eating habits. Everyone is hoping that something like that exists. And the commercials are promising that this time it is the pill that will work. And the hope and the suffering of being overweight makes people buy these pills. And then it doesn’t work again,”

The only upside to the study according to Ellrot was that none of the tested supplements had any negative side-effects. But he does point out that some unregulated weight-loss supplements found on the internet could be dangerous.

“I would warn people (not) to go anywhere else (than pharmacies) to shop for supplements. If they go onto the Internet and buy supplements somewhere in the world you could not be sure that this is a completely harmless thing. So, there are lots of mixtures of dangerous chemicals or compounds in dietary pills sold via the Internet.”

Ellrot stresses that only weight-loss supplements were tested in the research. There are a number of regulated weight-loss medications on the market which have had a proven effect. Many can only be obtained by prescription, but some are available over the counter.

Post by: Talk Drugs

British scientists has developed a type of pill containing lycopene and other ingredients, daily doses of one pill can help to reduce fat in blood vessels, help prevent cardiovascular disease.

This magical pellet developed by Cambridge University scientists, in addition to lycopene, it also contained whey, etc., which is helpful for absorbing by human bodies.

According to reports, lycopene quantity contained in a tomato pill is equivalent to that extracted from 3 kg tomatoes, and the initial human trials showed it has good health outcomes.

Based on the experiments upon150 heart patients carried by researchers, when patients taking daily dose of one tomato pill for 2 months, they can not only stop intaking pills but also reducing fat existed on arterial vascular walls, and has no side-effects.

Many studies have shown that the Italian-style diet – rich tomatoes, fish, vegetables, nuts and olive oil, is helpful to lower cholesterol significantly, and the same time helpful to prevent vascular disease.

You should pay 35 pounds per month to buy this magic pill per month .

As reported that researchers will continue to push forward large-scale experiments at Cambridge, the United States, Italy and Finland and other places this year.

Post by: Talk Drugs

We always make the point that, outside overt vitamin deficiencies for specific vitamins, which is kind of rare, just take in multivitamins there’s no evidence they will provide any benefits to your healthcare. And in fact lots of the studies which have been done have actually shown there’s a slight increase in cancers for taking multivitamins.

So what does Dr. Brassy tell his patients?

In the absence of any evidence, we do supply them if people really insist, but we certainly don’t offer them on a routine basis and we don’t really recommend them.

So what can we do, how can we make sure we get all the vitamins we need to stay healthy?

Lots of studies have shown over and over again, that a balanced diet will provide all the vitamins that a human needs under normal circumstances, and really it’s only in certain kind of very specific medical conditions that people do need to take vitamin supplements, from our point of view.

Be more cautious to take vitamin tablets, and a balanced diet means a bit of everything.

Post by: Talk Drugs

Today, researchers at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launch a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.

Although most cells in an organism share the same genetic information, different cell types, for example skin and liver cells, have different properties and functions, largely because different genes are active in these cells. The Gene Expression Atlas is a new database that allows users to query gene expression under a range of biological conditions, including different cell types, developmental stages, physiological states, phenotypes and disease states. The key questions this new database can answer can be summarised as:

1. under which conditions is my particular gene of interest expressed?
2. which genes are expressed in a particular condition? For example, what genes are specifically active in kidney cells, or how does the expression of genes in leukemic blood differ compared to normal blood?

Both questions can also be combined to focus on particular genes and their role in a specific disease, such as identifying members of the Wnt signalling pathway that are expressed in cancer.

The Atlas collates data from over 1000 different independent studies, mainly microarray experiments, with more than 30,000 samples in total. The new database is the latest product of the EBI’s Microarray Informatics group and has its origins in the EBI’s ArrayExpress resource. After a phase of development, the Atlas is ready to begin its own life as an independent major resource. Misha Kapushesky, Atlas project leader at the EBI commented, “While the ArrayExpress Archive makes data from high throughput functional genomics assays available to experts, Gene Expression Atlas presents this information in a format accessible to any biologist. The Atlas takes data directly from the ArrayExpress Archive, which is then enriched by curation, re-annotation and statistical computations before the results are presented to the user in an easily accessible form.”

The Gene Expression Atlas has already found use in the pharmaceuticals industry as a valuable research platform. The resource can be accessed from http://www.ebi.ac.uk/gxa and the Microarray Informatics group have produced an e-learning tutorial to guide users on how to get the most from the Atlas. This tutorial is freely available from the EBI’s e-learning portal at http://www.ebi.ac.uk/training/elearningcentral/.

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This year, the International Olympic Committee to take more stringent than in the past means to crack down on doping, but doping practices and types constant renovation. In September next year, Viagra may be on the prohibited list.

Recently, Viagra has been closely tracking by World Anti-Doping Agency (WADA). They are investigating whether Viagra is potential doping. And WADA has pointed out that some endurance athletes enhanced athletic ability through Viagra in Beijing Olympic Games.

Next month, the International Olympic Committee will re-test the Beijing Olympic Games athletes’ urine by the new method. The sports involved mainly are track and field, swimming and other endurance.

Samples of all the Beijing Olympic Games will be saved for 8 years, once new detection methods, the sample will be re-opened bottle at any time.