February 19th, 2009 -- Posted in Drug Tips |
30 minutes before and after taking medicine, you’d better not to eat anything, especially fruits and vegetables.
Experts ask us should drink much water after taking medicine, to promote the absorption of drugs. Vegetables and fruits contain a number of compounds and biological enzyme, these substances and drugs may react chemically, so that changes the drug effects.
Hypolipidemic, antibiotics, sleeping pills, caffeine, anti-allergy, etc., may be associated with certain substances in fruits and vegetables, so that drug failure, and even produced a strong drug toxicity.
February 19th, 2009 -- Posted in Drug Tips |
There are a lot of drugs (tablets) will take change in color after a long time. Some change from white to yellow or brown, but also becomes light brown.
These phenomena indicate that drugs have taken place in some kind of chemical changes. These changes may be due to the air of oxygen, sunlight exposure and other causes so that drug discoloration metamorphism, thus losing efficacy, even take place side effects.
February 18th, 2009 -- Posted in Drug Research |
Antipyretic analgesic drugs
These drugs such as aspirin, acetaminophen, ibuprofen, indomethacin, phenylbutazone poisoning can cause liver damage, etc. If the daily use of aspirin or more than 5 grams or use of acetaminophen more than 2 grams, they are easy to cause acute liver injury.
Antibiotics
These drugs such as macrolide drugs, sulfonamides, chloramphenicol, oxacillin, nystatin, chlorine lincomycin, tetracycline, ketoconazole, erythromycin and other tasteless can cause obvious liver damage. The abuse of oxacillin can cause toxic hepatitis in five days.
Gastrointestinal drugs
These drugs such as cimetidine, ranitidine and L-asparaginase can cause poisoning liver damage.
Cardiovascular drugs
These drugs such as methyldopa, quinidine, amiodarone, fenofibrate, lovastatin, etc. can cause liver damage. Among them, methyl dopa medication can damage the liver cells and ductular. A small number of patients in the use of methyl dopa jaundice and transaminase may be increased in 1 ~ 3 weeks, and may even happen granuloma-like hyperplasia of the liver, cirrhosis and liver necrosis.
Hypoglycemic agents
These drugs such as Delta, Culture and Sport, glybenclamide, Glurenorm etc may cause liver damage.
Sex hormones and contraceptive drugs
These drugs such as testosterone, male hormone, megestrol acetate, ethinyl estradiol, norethindrone and oral contraceptives can cause jaundice and other symptoms of liver damage.
Antineoplastic agents
These drugs such as azathioprine, methotrexate, 5 – fluorouracil, 6 – mercaptopurine, mitomycin, cyclophosphamide, etc. may cause liver damage. Among them, the emergence of drug azathioprine use the probability of jaundice could reach 20% ~ 40%; methotrexate can happen cirrhosis drug users; and mitomycin drug users can occur in severe liver damage.
Antipsychotic drugs
These drugs such as chlorpromazine, trifluoperazine may cause liver damage. 1% ~ 4% of the patients in the use of chlorpromazine will happen intrahepatic cholestasis in the 1 ~ 4 weeks, and some even will happen liver failure and death.
Antiepileptic drugs
These drugs such as phenytoin and sodium valproate can cause liver damage and so on.
Anti-tuberculosis drugs
These drugs such as isoniazid and rifampicin equality can cause liver damage. Isoniazid allergy drug in the use of 1 ~ 2 months later there will be severe hepatitis, liver necrosis and may even happen. If the isoniazid and rifampin combined use, it will greatly increase the liver toxicity of such drugs.
